HELP! I recently started chemo again for the third time in six years. I was put on exactly the same ( Paclitaxel and Carboplatin). I had my first session just over 3 weeks ago. I had a small reaction after the first cycle, bit of breathing difficulty and headaches, but nothing drastic. My oncologist deferred my second cycle until last week to make sure I was over the first lot. On Thursday last week, I went for my second cycle. No sooner had the Paclitaxel started going in and I had a MASSIVE reaction, I literally thought I was dying. My head felt like it was exploding, my spine was trying to fight it's way out of my back and I couldn't breathe for love nor money. Thankfully, all the staff on the unit were on me in seconds giving me god knows what. The thing is, after 5 days my body will not stop shaking and I feel constantly on the verge of tears. I just wondered has anyone else had a bad reaction to chemo, and how did it affect them, I just don't feel normal anymore.